William Lindsay Brandon (born c. 1801–1802 in Adams County, Mississippi; died October 8, 1890, in Wilkinson County, Mississippi) was a medical doctor, state legislator, planter and military officer best known for having served as a general in the Confederate States Army during the American Civil War. Brandon was born c. 1801–1802, though his exact birthdate is indeterminate.

Brandon served with the Confederate States Army from 1861 until 1864. He fought in several major battles, such as the Battle of Malvern Hill, where he was greatly injured after a ball passed through his ankle. He also participated in the Yorktown siege of 1862, the Battle of Williamsburg and the campaigns of Chattanooga and Knoxville. Brandon was promoted to the rank of brigadier general in June 1864. From July 1864 until the end of the war, he served in such positions as the commander of the Reserve Corps of Mississippi and the head of the Confederate Bureau of Conscription.

In his postbellum life, he returned to his Wilkinson County plantation where he worked, despite physical injury and age, until his death on October 8, 1890. Upon his death, he was buried at his plantation.  (light crease vertical in image, from the Fantastic Bill Turner collection)

Rare CDV Confederate General William L Brandon 21st Miss.